Author(s):
K. Durga Prasad, M. Sandhya Rani, D. Anusha
Email(s):
sandhya.madala@gmail.com
DOI:
10.5958/0974-4150.2018.00045.7 
Address:
K. Durga Prasad1, M. Sandhya Rani2*, D. Anusha2
1Natco Research Centre, Sanath Nagar, Hyderabad-500018
2Department of Pharmaceutical Chemistry, Pulla Reddy Institute of Pharmacy,
Gummadidala, Sangareddy, Telangana-502110
*Corresponding Author
Published In:
Volume - 11,
Issue - 2,
Year - 2018
ABSTRACT:
A new series of 1-methyl-2{[(3,4,5- tri substituted pyridine2-yl) methyl] sulfanyl}-5-nitro-1H-benzimidazoles 3a-3b were synthesized by coupling 1-methyl-2-mercapto-5-nitro-1H-benzimidazole 1 with various pyridine derivatives 2a-2b in the presence of a base at room temperature, Upon further oxidation of these Benzimidazole derivatives 3a-3b in presence of MCPBA gives 1-methyl-2{[(3,4,5- tri substituted pyridine2-yl) methyl] sulfinyl}-5-nitro-1H-benzimidazoles 4a-4b. The group frequencies of IR and NMR spectra were assigned.
Cite this article:
K. Durga Prasad, M. Sandhya Rani, D. Anusha. Synthesis, Characterization of Benzimidazole Derivatives carrying Pyridine Moiety. Asian J. Research Chem. 2018; 11(2):241-243. doi: 10.5958/0974-4150.2018.00045.7
Cite(Electronic):
K. Durga Prasad, M. Sandhya Rani, D. Anusha. Synthesis, Characterization of Benzimidazole Derivatives carrying Pyridine Moiety. Asian J. Research Chem. 2018; 11(2):241-243. doi: 10.5958/0974-4150.2018.00045.7 Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-2-5