Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Synthesis, Characterization of Benzimidazole Derivatives carrying Pyridine Moiety

Author(s): K. Durga Prasad, M. Sandhya Rani, D. Anusha

Email(s): sandhya.madala@gmail.com

DOI: 10.5958/0974-4150.2018.00045.7   

Address: K. Durga Prasad1, M. Sandhya Rani2*, D. Anusha2
1Natco Research Centre, Sanath Nagar, Hyderabad-500018
2Department of Pharmaceutical Chemistry, Pulla Reddy Institute of Pharmacy,
Gummadidala, Sangareddy, Telangana-502110
*Corresponding Author

Published In:   Volume - 11,      Issue - 2,     Year - 2018

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ABSTRACT:
A new series of 1-methyl-2{[(3,4,5- tri substituted pyridine2-yl) methyl] sulfanyl}-5-nitro-1H-benzimidazoles 3a-3b were synthesized by coupling 1-methyl-2-mercapto-5-nitro-1H-benzimidazole 1 with various pyridine derivatives 2a-2b in the presence of a base at room temperature, Upon further oxidation of these Benzimidazole derivatives 3a-3b in presence of MCPBA gives 1-methyl-2{[(3,4,5- tri substituted pyridine2-yl) methyl] sulfinyl}-5-nitro-1H-benzimidazoles 4a-4b. The group frequencies of IR and NMR spectra were assigned.


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Cite this article:
K. Durga Prasad, M. Sandhya Rani, D. Anusha. Synthesis, Characterization of Benzimidazole Derivatives carrying Pyridine Moiety. Asian J. Research Chem. 2018; 11(2):241-243. doi: 10.5958/0974-4150.2018.00045.7

Cite(Electronic):
K. Durga Prasad, M. Sandhya Rani, D. Anusha. Synthesis, Characterization of Benzimidazole Derivatives carrying Pyridine Moiety. Asian J. Research Chem. 2018; 11(2):241-243. doi: 10.5958/0974-4150.2018.00045.7   Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-2-5


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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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