Samir Derouiche, Taissir Cheradid, Messaouda Guessoum
Samir Derouiche, Taissir Cheradid, Messaouda Guessoum
Faculty of Natural and Life Sciences, El-Oued University, El Oued 39000, El Oued, Algeria.
Volume - 13,
Issue - 3,
Year - 2020
The aim of the current study is to evaluated the effect of drinking Water in Djamaa region on kidney function in rats. For this purpose, female Wistar rats divided into three groups (n=5), the first group of rats received mineral water serve as control, the second group of rabbits received tap water with (TDW) and the third group of rats received filtered water (FDW). Received drinking water for 60 days. Qualitative analysis of water showed a high level of chloride, calcium, potassium and sodium in TDW and low in FDW of Djamaa region as compared to mineral water. Our results showed a significant increase (p<0.05) of serum urea, creatinine and sodium levels and decrease in potassium and chloride in TDW and FDW group as compared to control. results obtained about hematological markers shows a significant decrease of Red blood cell (p<0.001), Hemoglobin (p<0.01), White blood cells (WBC) (p<0.001) and platelet (p<0.001) levels in TDW group compared to control. Results represent revealed also a significant increase (p<0.05) in MDA level and decreased (p<0.05) in antioxidant parameters such as GSH concentration, GST, SOD and catalase activities in TDW group as compared to control. In conclusion, this study showed that imbalance of electrolyte levels in tap water or filtered water is a major cause of kidney damage.
Cite this article:
Samir Derouiche, Taissir Cheradid, Messaouda Guessoum. Electrolyte Analysis of drinking water of Djamaa (Algeria) region and study its effect on the kidneys in Wistar rats. Asian J. Research Chem. 2020; 13(3):219-224. doi: 10.5958/0974-4150.2020.00042.5
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