Author(s):
Hindustan Abdul Ahad, Haranath Chinthaginjala, Syed Rahamtulla, Barji Prasanna Pallavi, Chakali Shashanka, Jangam Prathyusha
Email(s):
abdulhindustan@gmail.com
DOI:
10.52711/0974-4150.2021.00051 
Address:
Hindustan Abdul Ahad, Haranath Chinthaginjala, Syed Rahamtulla, Barji Prasanna Pallavi, Chakali Shashanka, Jangam Prathyusha
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu - 515001, AP, India.
*Corresponding Author
Published In:
Volume - 14,
Issue - 4,
Year - 2021
ABSTRACT:
The drugs of present use are lipophilic. Hence there is a need to surge the solubility of these drugs. To encounter this necessity one of the approaches is the formulation of drugs in form of Solid dispersions. Solid dispersions are a type of dispersion having one or extra one API in a torpid carrier at a solid state. We focused on the importance of solid dispersions in pharmaceutical formulation by using factorial design as it was easy to formulate. These solid dispersions are organized by several practises such as solvent technique, supercritical fluid technique and kneading tactic, etc., by referring the several journals, literature and pharmacy magazines we came to know that Solid dispersion are used to improve the solubility of the poor water-soluble drugs and also its bioavailability. At last, we conclude that through these Solid dispersions we can boost the Therapeutic efficiency of hydrophobic drugs by achieving greater solubility.
Cite this article:
Hindustan Abdul Ahad, Haranath Chinthaginjala, Syed Rahamtulla, Barji Prasanna Pallavi, Chakali Shashanka, Jangam Prathyusha. A Comprehensive report on Solid Dispersions by Factorial Design. Asian Journal of Research in Chemistry. 2021; 14(4):297-1. doi: 10.52711/0974-4150.2021.00051
Cite(Electronic):
Hindustan Abdul Ahad, Haranath Chinthaginjala, Syed Rahamtulla, Barji Prasanna Pallavi, Chakali Shashanka, Jangam Prathyusha. A Comprehensive report on Solid Dispersions by Factorial Design. Asian Journal of Research in Chemistry. 2021; 14(4):297-1. doi: 10.52711/0974-4150.2021.00051 Available on: https://ajrconline.org/AbstractView.aspx?PID=2021-14-4-12
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