Author(s):
Neetu Verma, Shruti Awasthi, Vikrant Jain
Email(s):
dr_vikrantjain@yahoo.in
DOI:
10.52711/0974-4150.2022.00027 
Address:
Neetu Verma1, Shruti Awasthi2, Vikrant Jain2
1Department of Chemistry, Faculty of Science and IT, Madhyanchal Professional University, Ratibad - 462044, Bhopal - Madhya Pradesh, India.
2Department of Chemistry, Government College, Khurai - 470117, Madhya Pradesh.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2022
ABSTRACT:
A novel series of novel 5-[(9H-carbazol-9-yl)methyl]-N-[(substituted phenyl)(piperazin-1-yl)methyl]-1,3,4-oxadiazol-2-amines (4a–o) products were synthesized from starting material of carbazole, which were on reacted with ethyl chloro-acetate yielded to form ethyl 2-(9H-carbazole-9-yl)acetate (1). Compound 1 on reacted with semicarbazide followed by cyclisation by sulphuric acid to give 5-((9H-carbazole-9-yl)-1,3,4-oxadiazol-2-amine (3), which through Mannich condensation with piperazine and a variety of aromatic aldehydes in the occurrence of acetic acid to form titled compounds (4a–o). The structures of compounds were characterized by UV, FT-IR, 1H-NMR and MS spectral studies, and by elemental analysis.
Cite this article:
Neetu Verma, Shruti Awasthi, Vikrant Jain. Synthesis, Characterization and Biological Screening of some Newer Carbazole Conjugates. Asian Journal of Research in Chemistry. 2022; 15(2):163-5. doi: 10.52711/0974-4150.2022.00027
Cite(Electronic):
Neetu Verma, Shruti Awasthi, Vikrant Jain. Synthesis, Characterization and Biological Screening of some Newer Carbazole Conjugates. Asian Journal of Research in Chemistry. 2022; 15(2):163-5. doi: 10.52711/0974-4150.2022.00027 Available on: https://ajrconline.org/AbstractView.aspx?PID=2022-15-2-11
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