S.R. Bavaskar, A.D. Agrawal, Y.S. Agrawal, A.N. Amrutkar, Niraj L. Badhe, P.S. Kawatikwar
S.R. Bavaskar*, A.D. Agrawal, Y.S. Agrawal, A.N. Amrutkar, Niraj L. Badhe and P.S. Kawatikwar
Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jammer Dist-Jalgaon 424206
Volume - 3,
Issue - 3,
Year - 2010
A simple, sensitive, accurate and precise UV Spectrophotometric method has been developed for quantitative determination of Tramadol Hydrochloride in bulk and tablet formulations. The UV- spectrum was scanned between 220 to 400 nm and 270.5 nm was selected as maximum wavelength for absorption. Tramadol shows molar absorptivity of 1.771×104l/mol/cm and Sandell’s sensitivity 0.16927mcg/Sq.cm/0.001-absorbance units. Beer’s law was obeyed in the concentration range of 15-170 µg/ml. Results of analysis were validated statistically and by recovery studies.
Cite this article:
S.R. Bavaskar, A.D. Agrawal, Y.S. Agrawal, A.N. Amrutkar, Niraj L. Badhe, P.S. Kawatikwar. Spectrophotometric Estimation of Tramadol Hydrochloride in Bulk and Tablet Dosage Form. Asian J. Research Chem. 3(3): July- Sept. 2010; Page 714-715.