ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): RB Kakde, VH Kotak, DL Kale

Email(s): drkakde@yahoo.com

DOI: Not Available

Address: RB Kakde*, VH Kotak and DL Kale
Department of Pharmaceutical Sciences, RTM Nagpur University Nagpur-440033 (MS) India.
*Corresponding Author

Published In:   Volume - 1,      Issue - 2,     Year - 2008


ABSTRACT:
A novel analytical method for determination of bisoprolol fumarate in tablet dosage form has been developed by HPTLC procedure, using Methanol: Toluene: Ammonia (2:4:0.1, v/v/v) as mobile phase and Merck HPTLC plate precoated 60 F254 silica gel on aluminum sheet as stationary phase. Detection was carried out densitometrically using UV detector at 229 nm. The retention factor (Rf) of bisoprolol fumarate was 0.52±0.02. The linear regression analysis data was used for the regression line in the range of 500-1000 ng/spot for bisoprolol fumarate with correlation coefficient value close to 1.0. The developed method was validated using various validation parameters such as accuracy, precision, specificity, limit of detection, limit of quantitation and ruggedness, which make method as choice for routine quality control analysis for estimation of bisoprolol fumarate in tablet formulation.


Cite this article:
RB Kakde, VH Kotak, DL Kale. Estimation of Bisoprolol Fumarate in Pharmaceutical Preparations by HPTLC. Asian J. Research Chem. 1(2): Oct.-Dec. 2008; Page 70-73.


Recomonded Articles:

Author(s): Bulusu Lakshmi Sushma1, Gutta Madhusudhan, Anireddy Jayashree

DOI: 10.5958/0974-4150.2017.00014.1         Access: Open Access Read More

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

Author(s): Ismail, R Rajavel, M Ganesh, M Jagadeeswaran, K Srinivasan, J Valarmathi, T Sivakumar

DOI:         Access: Open Access Read More

Author(s): Suman Bala, Minaxi Saini, Sunil Kamboj, Goldie Uppal, Ashok Kumar

DOI:         Access: Open Access Read More

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): Anilkumar Kodge, Arunkumar lagashetty

DOI: 10.5958/0974-4150.2017.00023.2         Access: Open Access Read More

Author(s): VB Kshirsagar, UA Deokate, VB Bharkad, SS Khadabadi

DOI:         Access: Open Access Read More

Author(s): Mukund Nagarnaik, Arun Sarjoshi, Ajay Bodkhe, Bhupendra Khanal, Mayuri Pise, Girish Pandya

DOI: 10.5958/0974-4150.2015.00102.9         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Author(s): Satish. Y. Mane, D.V. Mane

DOI: 10.5958/0974-4150.2017.00019.0         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags