Suresh Rajput, Dharamveer Sisodia, Hemant Badwaik, Deepa Thakur, Kushagra Nagori
Suresh Rajput1, Dharamveer Sisodia1, Hemant Badwaik2*, Deepa Thakur2 and Kushagra Nagori2
1Ultra College of Pharmacy, Madurai (T.N)
2Rungta College of Pharmaceutical Sciences and Research, Bhilai (C.G)
Volume - 4,
Issue - 1,
Year - 2011
A novel 5(4-(4-substituted)Aminobenzylidine)thiazolidine-2,4-dione derivatives were synthesized and characterized by IR and H-NMR spectral analysis. Antibacterial and antifungal activities of the compounds were assessed by in vitro growth inhibitory activity against Escherichia coli, Staphylococcus aureus, Asperigillus niger, Candida albicans by using the disc diffusion method. Most of all compounds exhibited significant antibacterial activity against Staphylococcus aureus and Escherichia coli, while weak antifungal activity against Asperigillus niger and Candida albicans.
Cite this article:
Suresh Rajput, Dharamveer Sisodia, Hemant Badwaik, Deepa Thakur, Kushagra Nagori. Synthesis, Characterization and Antimicrobial Activity of a 5(4-(4-Substituted)Aminobenzylidine)Thiazolidine-2,4-Dione Derivatives. Asian J. Research Chem. 4(1): January 2011; Page 40-43.