Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Synthesis and Characterization of Hydrazones, Pyrazoles and Pyrazolones from 8-Amino-6-Chloro Coumarine

Author(s): Ashok G. Gadre, V.V. Nawathye, D.B. Dalavi, D. J. Upadhyaya, B. R. Thorat, R. S. Yamgar

Email(s): bthorat78@gmail.com

DOI: Not Available

Address: Ashok G. Gadre, V.V. Nawathye, D.B. Dalavi, D. J. Upadhyaya, B. R. Thorat* and R. S. Yamgar
Chemistry Research Laboratory, Patkar-Varde College, Goregaon (W), Mumbai 62.
*Corresponding Author

Published In:   Volume - 4,      Issue - 10,     Year - 2011

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ABSTRACT:
8-Amino-6-chlorocoumarine has been synthesized by multistep synthesis which involves the successive chlorination and nitration of salicylaldehyde. The coumarin was synthesized by using Perkin reaction. The resulting nitro-compound can be reduced to 8-amino-6-chlorocoumarine. This was then diazotized and then coupled with different ß-diketones and ß-ketoesters gives corresponding hydrazones. The hydrazones were cyclized by reacting with hydrazines to get pyrazole and pyrazolone derivatives.


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Cite this article:
Ashok G. Gadre, V.V. Nawathye, D.B. Dalavi, D. J. Upadhyaya, B. R. Thorat, R. S. Yamgar. Synthesis and Characterization of Hydrazones, Pyrazoles and Pyrazolones from 8-Amino-6-Chloro Coumarine. Asian J. Research Chem. 4(10): Oct., 2011; Page 1621-1624.

Cite(Electronic):
Ashok G. Gadre, V.V. Nawathye, D.B. Dalavi, D. J. Upadhyaya, B. R. Thorat, R. S. Yamgar. Synthesis and Characterization of Hydrazones, Pyrazoles and Pyrazolones from 8-Amino-6-Chloro Coumarine. Asian J. Research Chem. 4(10): Oct., 2011; Page 1621-1624.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2011-4-10-29


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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