Author(s):
S. B. Salve, C. J. Patil, H. A. Mahajan
Email(s):
sanjivsalve@gmail.com , drcjpatil@yahoo.com
DOI:
10.5958/0974-4150.2018.00058.5 
Address:
S. B. Salve, C. J. Patil, H. A. Mahajan
Smt. G. G. Khadse College, Muktainagar, Dist-Jalgaon-425 306, M.S., India
*Corresponding Author
Published In:
Volume - 11,
Issue - 2,
Year - 2018
ABSTRACT:
The condensed reaction of aromatic ketone, 5-Chloro-2-hydroxy-4-methyl-acetophenone with aniline and its derivatives each separately viz. Aniline, 4-Amino-phenol, 2-Amino-thiophenol, 4-Amino-thiophenol, 4-Chloro-2-nitro-aniline, 2-Amino-benzonitrile and 4-Amino-benzonitrile and reacted efficiently to produced a series of ketimines in high yield and purity. These were analyzed by employing the TLC technique. All the products were characterized by their colour, physical constant, TLC, elemental analysis and spectral(UV-Vis and FTIR) method. After confirming their desired molecular studies, these ketimines were studied for their antifungal activity using A. alternata, and F. oxysporum.
Cite this article:
S. B. Salve, C. J. Patil, H. A. Mahajan. Studies on Synthesis of Aromatic Schiff Bases. Part-VI. Synthesis, Characterization and Biological Activity of Ketimines from 5-Chloro-2-hydroxy-4-methyl-acetophenone with substituted anilines. Asian J. Research Chem. 2018; 11(2):312-318. doi: 10.5958/0974-4150.2018.00058.5
Cite(Electronic):
S. B. Salve, C. J. Patil, H. A. Mahajan. Studies on Synthesis of Aromatic Schiff Bases. Part-VI. Synthesis, Characterization and Biological Activity of Ketimines from 5-Chloro-2-hydroxy-4-methyl-acetophenone with substituted anilines. Asian J. Research Chem. 2018; 11(2):312-318. doi: 10.5958/0974-4150.2018.00058.5 Available on: https://ajrconline.org/AbstractView.aspx?PID=2018-11-2-18