Asian Journal of Research in Chemistry

ISSN

0974-4150 (Online)
0974-4169 (Print)


Submit Article

Synthesis of some New Pyrimidines from Chalcone Containing an Imin Group

Author(s): Hanan Falih Mohsin

Email(s): hanan.alshebly@uokufa.edu.iq

DOI: Not Available

Address: Hanan Falih Mohsin
Department of Chemistry, College of Education for Girls, University of Kufa, Najaf, Iraq
*Corresponding Author

Published In:   Volume - 6,      Issue - 9,     Year - 2013

 View HTML        View PDF

ABSTRACT:
In this present study, p-amino acetophenone condensed with p-nitro benzaldehyde in ethanolic solution of sodium hydroxide to yield corresponding chalcone, which reacts with various aromatic aldehydes in glacial acetic acid to yield corresponding Schiff bases. These chalcones were further reacted with urea, thiourea, guanedin in the presence of base in ethanol, which led to the formation of pyrimidine derivatives. Thin layer chromatography was used to follow the reactions. All the compounds have been characterized by FT-IR Spectroscopy, some of them characterized by (1H -NMR)-spectra and elemental analysis (C.H.N).


Keywords:

Cite this article:
Hanan Falih Mohsin. Synthesis of some New Pyrimidines from Chalcone Containing an Imin Group. Asian J. Research Chem. 6(9): September 2013; Page 849-854.

Cite(Electronic):
Hanan Falih Mohsin. Synthesis of some New Pyrimidines from Chalcone Containing an Imin Group. Asian J. Research Chem. 6(9): September 2013; Page 849-854.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2013-6-9-11


Recomonded Articles:

Herbal tea for the treatment of Urinary diseases as Potent diuretic and Anti-inflammatory agent

Author(s): Kateryna Taran, Ayaou Abderrahim, Vera Kravchenko, Olena Novosel, Svitlana Taran

DOI: 10.5958/0974-4150.2020.00034.6         Access: Open Access Read More

Method Development and Validation for Simultaneous Estimation of Metamizole Sodium and Pitofenone HCl by a Stability Indicating RP-HPLC

Author(s): R. Vijayalakshmi, S. Anbazhagan

DOI:         Access: Open Access Read More

Application of Chalcones in Synthesis of Novel 1, 5-Benzodiazepine Derivatives Containing Thieno [2, 3-d] Pyrimidine Core Unit and its Biological Activity Screening

Author(s): Virupakshi Prabhakar, Kondra Sudhakar Babu, L.K. Ravindranath, M. Sahanoor Basha, J. Latha

DOI: 10.5958/0974-4150.2017.00012.8         Access: Open Access Read More

Forced degradation study of Terbinafine HCl by HPLC with PDA detector

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

A Review Article on Flash Chromatography

Author(s): Sravani A

DOI: 10.5958/0974-4150.2018.00144.X         Access: Open Access Read More

A New Simple RP – HPLC Method for Simultaneous Estimation of Meropenem and Vaborbactam in Tablet Dosage Form

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Stability Indicating RP- HPLC Method for Simultaneous Estimation of Valsartan and Amlodipine in Capsule Formulation.

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Detection of Commonly used Carbamates by Thin Layer Chromatography and Spot Test Method

Author(s): Subhasish Chaudhur, Biswajit Chandra Das

DOI:         Access: Open Access Read More

Pharmacognostic and Preliminary Phytochemical Screening of Cichorium intybus Linn Seed

Author(s): Tauseef Shaikh, Atar Mujum , Khan Wasimuzzama, Rukhsana A Rub

DOI:         Access: Open Access Read More

Critical review: Significance of Force degradation study with respect to current Pharmaceutical Scenario

Author(s): Nikita N. Patel, Charmy S. Kothari

DOI:         Access: Open Access Read More

Gas Chromatography Mass Spectrometry Analysis of Andrographis paniculata

Author(s): N. Prabha, J. Rahmath Bushra

DOI: 10.5958/0974-4150.2019.00001.4         Access: Open Access Read More

Synthesis, characterization and pharmacological evaluation of novel spiro heterocyclic compounds as anti diabetic agents

Author(s): K. Kishore Kumar, R.S.K. Sharma, P. Chanti Babu, M. Sreenivasa Rao, K. Durga Prasadu, D. Ravi Kumar

DOI: 10.5958/0974-4150.2017.00067.0         Access: Open Access Read More

Isolation and Structure Characterization of related impurity in Olanzapine key starting material by LC/ESI-MS and NMR

Author(s): Jagadeesh Narkedimilli, Vishweshwar Vavilala, Sandeep Mohanty, Saravanan Manvalan, Jayashree Anireddy

DOI: 10.5958/0974-4150.2018.00096.2         Access: Open Access Read More

Design, Synthesis, Structural Elucidation and Antimicrobial Screening of Novel 1, 5-Benzothiazepine derivatives Derived from Thieno [3, 2-d] Pyrimidine Nucleus

Author(s): Virupakshi Prabhakar, Kondra Sudhakar Babu, L.K. Ravindranath, J. Latha, B.Venkateswarlu

DOI: 10.5958/0974-4150.2017.00011.6         Access: Open Access Read More

Simultaneous Determination of Strychnine and Brucine in Herbal Formulation by RP-HPLC

Author(s): Babu Ganesan, Perumal Perumal, Vijaya Baskaran Manickam, Surya Rao Srikakolapu, Srujana Divya Gotteti, Latha Sundaresan Thirumurthy

DOI:         Access: Open Access Read More

Molecular docking studies and ADMET Predictions of Pyrimidine Coumarin Scaffolds as Potential IDO Inhibitors

Author(s): Radhika Chelamalla, Ajitha Makula

DOI: 10.5958/0974-4150.2017.00056.6         Access: Open Access Read More

Phyto-Physico chemical evaluation, Antioxidant activities and Diuretic activity of Leaves of Lagerstroemia reginae

Author(s): S Kalidas, B Kameswari, P Devi, B Madhumitha, R Meera, NJ Merlin

DOI:         Access: Open Access Read More

Analytical Method Development and Validation of Cefixime and Dicloxacillin Tablet by RP-HPLC

Author(s): Kathiravan S., Anbarasi B., Mathankumar S.

DOI:         Access: Open Access Read More

Simultaneous Determination of Sodium Benzoate and Potassium Sorbate Preservatives in Foodstuffs Using High-Performance Liquid Chromatography

Author(s): Antakli S, Alahmad A, Badingki H

DOI:         Access: Open Access Read More

Phytochemical screening and column chromatography studies of Aerva lanata

Author(s): A. Anita, A. Malar Retna, J. Joseph

DOI: 10.5958/0974-4150.2018.00019.6         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Quick Links

Latest Issues

Popular Articles


Recent Articles



Activated carbon from macadamia nutshells for removal of p-Nitrophenol from real wastewater: Thermodynamic evaluation
Review on Colon Targeted Drug Delivery System
Exploring the Effects of Polyacrylic Acid on Triton-X-100 Aqueous Solutions: Density, Viscosity and Ultrasonic Velocity Analysis
Formulation and Evaluation of Amaranthus dubius herbal gel
Estimation of Imatinib Mesylate by Extractive Colorimetric Methods in Bulk and Pharmaceutical Dosage Form
Qualitative and Quantitative Analysis of the Phytochemicals in Aerva lanata
Co-Solvent effect and Kinetics of Alkaline Hydrolysis of Butyle Salicylate
A Systematic Review on Ethnobotanical and Pharmacological Aspects of Croton plant Codiaeum variegatum (L.)
Review on Thiazolo-Triazole as a Promising Anticancer agent
Inimical effects of Monosodium Glutamate on various systems
Synthesis and Surface properties of LABSA Based detergents: An Ecofriendly Approach
A mini Review on Analytical and Bioanlytical Techniques in Study of Drugs-Protein Interaction
Review on Vesicular Drug Delivery System: Aquasomes
Synthesis, Characterization and Antioxidant Activity of some New Antipyrine derived Schiff Bases
Determination of Imatinib mesylate from Pharmaceutical Dosage Form by extractive ion pair complex colorimetric Method
Coupling of Single-Stranded poly-T DNA with Small Heterocyclic compounds via Peptide Linkage
Determination of Methdilazine by Extractive Colorimetric Method from Pharmaceutical Dosage Form
Synthesis and Surface properties of AOS Based detergents: A Green Synthetic approach
Bioanalytical Method Development and Validation of UV Spectrophotometric Method for Estimation of Metformin Hydrochloride in Urine Sample
Oxovanadium (IV) Complexes of α-Amino Acid Schiff Bases and 2,2

Tags


About Journal

Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
Read More  

Visitors

Today: 184
Yesterday: 1473
Total: 1570977