Asian Journal of Research in Chemistry

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0974-4169 (Print)


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Microwave Assisted Facile Synthesis of Some Novel Mannich’s Bases of Isatoic Anhydide Derivatives

Author(s): Veena Yadav, Nishant Yadav

Email(s): veenayadav2006@gmail.com

DOI: Not Available

Address: Veena Yadav* and Nishant Yadav
Department of Chemistry, Kurukshetra University, Kurukshetra (India)
*Corresponding Author

Published In:   Volume - 4,      Issue - 4,     Year - 2011

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ABSTRACT:
An efficient microwave assisted protocol for the synthesis of Mannich’s bases of isatoic-anhydride derivatives 4(a-g) has been described. Treatment of isatoic anhydride (1) with formaldehyde yielded 1-hydroxymethyl-1H-benzo[d][1,3]oxazine-2,4-dione (2) followed by reaction with HCl afforded 1-chloromethyl-1H-benzo[d][1,3]oxazine-2,4dione (3) which reacted smoothly with sec. amines to give mannich’s bases 4(a-g) in excellent yield.


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Cite this article:
Veena Yadav, Nishant Yadav. Microwave Assisted Facile Synthesis of Some Novel Mannich’s Bases of Isatoic Anhydide Derivatives. Asian J. Research Chem. 4(4): April, 2011; Page 626-628.

Cite(Electronic):
Veena Yadav, Nishant Yadav. Microwave Assisted Facile Synthesis of Some Novel Mannich’s Bases of Isatoic Anhydide Derivatives. Asian J. Research Chem. 4(4): April, 2011; Page 626-628.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2011-4-4-25


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Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

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DOI: 10.5958/0974-4150 

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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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