Virupakshi Prabhakar, B.Venkateswarlu, Punagani Bhargavi, Sura Jagadeesh
Virupakshi Prabhakar1*, B.Venkateswarlu2, Punagani Bhargavi3, Sura Jagadeesh3
1SVR Engineering College, Jawaharlal Nehru Technological University (JNTU-A), Nandyal, Kurnool (Dist), A.P., 518502 INDIA.
2PBR VITS, Jawaharlal Nehru Technological University (JNTU-A), Kavali, Nellore (Dist), (A.P.) INDIA.
3Prajna Solutions Pvt. Ltd., Hyderabad, Telangana, India
Volume - 9,
Issue - 10,
Year - 2016
Quinazoline nucleus is present in various compounds and it is responsible for diverse biological activities. The present work mainly focused on the Quinazolines with potential activities that are now in development. The objective of this research work is to synthesize various compounds containing Quinazoline moiety and their derivatives as well as characterising the compounds by spectral analysis and screening for antimicrobial and anticancer activities. The structures of synthesized compounds were confirmed by various spectroscopic methods such as IR, NMR and mass spectroscopy. The products were evaluated for their antimicrobial activity against several microbes. Some of the compounds exhibited potent anti-bacterial activity as well as anti-fungal activity. Among the Novel Quinazoline derivatives 8i, 8j, 8d shows Excellent Anti-microbial activity.
Cite this article:
Virupakshi Prabhakar, B.Venkateswarlu, Punagani Bhargavi, Sura Jagadeesh. Design, Synthesis and Activity of Novel Quinazoline Derivatives Linked with various Sulphonamides. Asian J. Research Chem. 2016; 9(10):485-504. doi: 10.5958/0974-4150.2016.00073.0