ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Rajan V. Rele, Prathamesh P. Tiwatane

Email(s): drvinraj@gmail.com

DOI: 10.5958/0974-4150.2018.00051.2   

Address: Rajan V. Rele, Prathamesh P. Tiwatane
Central Research Laboratory, D.G. Ruparel College, Matunga, Mumbai , 400 016.
*Corresponding Author

Published In:   Volume - 11,      Issue - 2,     Year - 2018


ABSTRACT:
The validation of omeprazole from combined dosage form i.e. tablets was described by high performance liquid chromatography method with separation of drugs on BDS Hypersil C18 (150 x 4.6 mm i.d.) and 5 µ particle size. A mixture of buffer and acetonitrile (65:35 % (v/v)) was constituted as mobile phase. The chromatograms were studied at 230 nm as wavelength. The mobile phase was also used as a diluent. A validated of method was studied for linear regression, accuracy, method as well as system precision. The robustness study was done for change in wavelength, mobile phase composition and flow rate as per ICH guidelines. The method has been successfully used to analyze omeprazole from dosage form i.e. tablets and drotaverine from combined dosage form i.e. tablets.


Cite this article:
Rajan V. Rele, Prathamesh P. Tiwatane. Reverse Phase High Performance Liquid Chromatography for Method Development Validation of Omeprazole in Bulk and Pharmaceutical Dosage Form. Asian J. Research Chem. 2018; 11(2):275-278. doi: 10.5958/0974-4150.2018.00051.2


Recomonded Articles:

Author(s): Kateryna Taran, Ayaou Abderrahim, Vera Kravchenko, Olena Novosel, Svitlana Taran

DOI: 10.5958/0974-4150.2020.00034.6         Access: Closed Access Read More

Author(s): Tauseef Shaikh, Atar Mujum , Khan Wasimuzzama, Rukhsana A Rub

DOI:         Access: Open Access Read More

Author(s): SS Chitlange, Kiran Bagri, DM Sakarkar

DOI:         Access: Open Access Read More

Author(s): B. Balaswami, P. Venkata Ramana, B. Subba Rao, P. Sanjeeva

DOI: 10.5958/0974-4150.2018.00023.8         Access: Open Access Read More

Author(s): Tentu Nageswara Rao, Muralidhar Reddy Avuthu, B. Venkata Reddy, SNVS Murthy

DOI: 10.5958/0974-4150.2016.00076.6         Access: Open Access Read More

Author(s): Sravani A

DOI: 10.5958/0974-4150.2018.00144.X         Access: Open Access Read More

Author(s): K. Kishore Kumar, R.S.K. Sharma, P. Chanti Babu, M. Sreenivasa Rao, K. Durga Prasadu, D. Ravi Kumar

DOI: 10.5958/0974-4150.2017.00067.0         Access: Open Access Read More

Author(s): Babu Ganesan, Perumal Perumal, Vijaya Baskaran Manickam, Surya Rao Srikakolapu, Srujana Divya Gotteti, Latha Sundaresan Thirumurthy

DOI:         Access: Open Access Read More

Author(s): Kathiravan S., Anbarasi B., Mathankumar S.

DOI:         Access: Open Access Read More

Author(s): S Kalidas, B Kameswari, P Devi, B Madhumitha, R Meera, NJ Merlin

DOI:         Access: Open Access Read More

Author(s): Nikita N. Patel, Charmy S. Kothari

DOI:         Access: Open Access Read More

Author(s): Subhasish Chaudhur, Biswajit Chandra Das

DOI:         Access: Open Access Read More

Author(s): Jagadeesh Narkedimilli, Vishweshwar Vavilala, Sandeep Mohanty, Saravanan Manvalan, Jayashree Anireddy

DOI: 10.5958/0974-4150.2018.00096.2         Access: Open Access Read More

Author(s): K. Balamuralikrishna, B. Syamasundar

DOI:         Access: Open Access Read More

Author(s): Cijo John, Mohd Idris, P. Sudhakar, Priyankar Ghosh, K.M. Varshney, S.K. Shukla

DOI:         Access: Open Access Read More

Author(s): P Nagaraju, K Krishnachaithanya, VDN Srinivas, SVN Padma

DOI:         Access: Open Access Read More

Author(s): C.K.Oza, Ranju Nijhawan, M. K. Pandya, A. J. Vyas, A. I. Patel

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags