Author(s):
Namita Bhardwaj, Pratyush Jaiswal, Jaishri Kaushik
Email(s):
pratyush.jaiswal08shanu@gmail.com
DOI:
10.52711/0974-4150.2024.00028
Address:
Namita Bhardwaj1, Pratyush Jaiswal2*, Jaishri Kaushik3
1Professor, Department of Chemistry, Dr C V Raman University, Kota, Bilaspur, Chhattisgarh, India.
2Ph.D. Scholar, Dr C V Raman University, Kota, Bilaspur, Chhattisgarh, India.
3Assistant Professor, LCIT College of Commerce and Science, Bodari, Bilaspur, Chhattisgarh, India.
*Corresponding Author
Published In:
Volume - 17,
Issue - 3,
Year - 2024
ABSTRACT:
The current study's objective was to use both qualitative and quantitative screening techniques to determine whether phytochemicals were present in the methanolic, ethanolic, and aqueous extracts of Aerva lanata. Standard techniques were used to analyze the phytochemical compounds present in crude extracts, including steroids, terpenoids, phlobatannins, reducing sugar, triterpenoids, alkaloids, phenolic compounds, flavonoids, saponins, quinones, oxalates, tannins, cardiac glycosides, and anthraquinones. The methanolic extracts showed positive results for the maximum number of phytochemical compounds. In quantitative analysis, the essential secondary metabolites such as phenolic compounds, flavonoids, tannins, carbohydrates, alkaloids, saponins, phenols, and terpenoids were tested in all three solvent extracts of the leaf. The methanolic extract of the leaf showed the highest amounts of phytochemicals when compared with other solvent extracts.
Cite this article:
Namita Bhardwaj, Pratyush Jaiswal, Jaishri Kaushik. Qualitative and Quantitative Analysis of the Phytochemicals in Aerva lanata. Asian Journal of Research in Chemistry. 2024; 17(3):149-5. doi: 10.52711/0974-4150.2024.00028
Cite(Electronic):
Namita Bhardwaj, Pratyush Jaiswal, Jaishri Kaushik. Qualitative and Quantitative Analysis of the Phytochemicals in Aerva lanata. Asian Journal of Research in Chemistry. 2024; 17(3):149-5. doi: 10.52711/0974-4150.2024.00028 Available on: https://ajrconline.org/AbstractView.aspx?PID=2024-17-3-5
REFERENCES:
1. Rajesh R, Chitra K, Paarakh PM. Antihyperglycemic and anti-hyperlipidemic activity of aerial parts of A. lanata Linn Juss in streptazotocin induced diabetic rats, Asian Journal of Tropical Biomedicine. 2012; 2(2): 5924-9. DOI:10.1016/S2221-1691(12)60338-4
2. Mammen D, Daniel M, Sane RT. Variations in Values of Proximate Analysis in Aerva Lanata Juss Ex Schultes, Hedyotis Corymbosa (L.) Lam. And Leptadenia Reticulata (Retz.) W. & A. International Journal of Pharma and Biosciences. 2010; 1(4): 629-36.
3. Rajesh R, Chitra K, Padmaa PM. Anthelmintic activity of aerial parts of Aerva lanata Linn Juss. International Journal of Pharmaceutical Sciences and Drug Research. 2010; 2(4): 269-71. https://ijpsdr.com/index.php/ijpsdr/article/view/149.
4. Hasler CM, Blumberg JB. Symposium on Phytochemicals, Biochemistry and Physiology. Journal of Nutrition. 1999; Mar 129: 756-7. DOI: 10.1093/jn/129.3.756S
5. Gibson EL, Wardel J, Watts CJ. Fruit and Vegetable Consumption, Nutritional Knowledge and Beliefs in Mothers and Children. Appetite. 1998; 31: 205-28. DOI: 10.1006/appe.1998.0180
6. Mathai K. Nutrition in the Adult Years, In Krause’s Food, Nutrition, and Diet Therapy, 10th edition, edited by L K Mahan and S Escott-Stump, W.B. Saunders Company, Pennsylvania. 2000.
7. Costa MA, Zia ZQ, Davin LB, Lewis NG. Chapter Four: Toward Engineering the Metabolic Pathways of Cancer-Preventing Lignans in Cereal Grains and Other Crops, In Recent Advances in Phytochemistry (Phytochemicals in Human Health Protection, Nutrition, and Plant Defense, ed. JT Romeo, New York. 1999.
8. Narasinga R. Bioactive phytochemicals in Indian foods and their potential in health promotion and disease prevention. Asia Pacific Journal of Clinical Nutrition. 2023; 12(1): 9-22. https://pubmed.ncbi.nlm.nih.gov/12737006/
9. Kumar G, Karthik L, Rao BKV. Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. ex Schult. Stem (Amaranthaceae). Asian Pacific Journal Tropical Medicine. 2013: 180-7. DOI: 10.1016/S1995-7645(13)60020-6
10. Ragavendran P, Sophia D, Arul Raj C, Starlin T, Gopalakrishnan VK. Phytochemical screening, antioxidant activity of Aerva lanata (L)- An in vitro study. Asian Journal of Pharmaceutical and Clinical Research. 2012: 77-81.https://www.researchgate.net/publication/279670373_Phytochemical_screening_antioxidant_activity_of_Aerva_lanata_lAn_invitro_study
11. Ragavendran P, Sophia D, Raj CA, Starlin T, Gopalakrishnan VK. Evaluation of enzymatic and non-enzymatic antioxidant properties of Aerva lanata (L)- An in vitro study. International Journal of Pharmacy and Pharmaceutical Science. 2012: 522-6. https://www.researchgate.net/publication/285350379_Evaluation_of_enzymatic_and_non-enzymatic_antioxidant_properties_of_Aerva_lanata_L_-an_Invitro_study
12. Nevin KG, Vijayammal PL. Effect of Aerva lanata against hepatotoxicity of carbon tetrachloride in rats. Environmental Toxicology and Pharmacology. 2005 Nov 20: 471-7. DOI: 10.1016/j.etap.2005.05.010
13. Nevin KG, Vijayammal PL. Pharmacological and Immunomodulatory Effects of Aerva lanata in Daltons Lymphoma Ascites–Bearing Mice. Pharmaceutical Biology. 2008; Oct 43: 640-6. doi.org/10.1080/13880200500303858
14. Sharma A, Tarachand, Tanwar M, Nagar N, Sharma AK. Analgesic and anti-inflammatory activity of flower extract of Aerva lanata. Advance Pharmacology Toxicology. 2012; Jan 12: 13-8. https://www.researchgate.net/publication/232716747_Analgesic_and_anti-inflammatory_activity_of_flowers_extract_of_Aervalanata
15. Balasuriya GMGK, Dharmaratne HRW. Cytotoxicity and antioxidant activity studies of green leafy vegetables consumed in Sri Lanka. Journal of the National Science Foundation of Sri Lanka. 2007 Dec 35: 255-8. doi :10.4038/jnsfsr.v35i4.1315
16. Ramachandra YL, Shilali K, Ahmed M, Sudeep HV, Kavitha BT, Gurumurthy H, Rai SP. Hepatoprotective properties of Boerhaavia diffusa and Aerva lanata against carbon tetra chloride induced hepatic damage in rats. Pharmacology Online. 2011 Jan 3: 435-41. https://www.researchgate.net/publication/286036749_Hepatoprotective_properties_of_boerhaavia_diffusa_and_Aerva_lanata_against_carbon_tetra_chloride_induced_hepatic_damage_in_rats
17. Shirwaikar A, Issac D, Malini S. Effect of Aerva lanata on cisplatin and gentamicin models of acute renal failure. Journal of Ethnopharmacology. 2004; Jan 90: 81-6. DOI: 10.1016/j.jep.2003.09.033
18. Kumar KS, Prabhu SN, Ravishankar B, Sahana Yashovarma Y. Chemical analysis and in vitro evaluation of antiurolithiatic activity of Aerva lanata (Linn.) Juss. Ex Schult. Roots. Research and Review: Journal of Pharmacognosy Phytochemistry. 2015; July 3: 1-7. https://www.rroij.com/open-access/chemical-analysis-and-in-vitro-evaluation-ofantiuro lithiatic -activity of- aerva-lanata-linn-juss-ex-schult-roots.php?aid=56328
19. Rajesh R, Chitra K, Paarakh PM. Anti hyperglycemic and antihyperlipidemic activity of aerial parts of Aerva lanata Linn Juss. in streptozotocin-induced diabetic rats. Asian Pacific Journal of Tropical Biomedicine. 2012; Feb 2(2): 924-9. DOI:10.1016/S2221-1691(12)60338-4
20. Riya MP, Antu KA, Pal S, Chandrakanth KC, Anilkumar KS, Tamrakar AK, Srivastava AK, Raghu KG. Antidiabetic property of Aerva lanata (L.) Juss. ex Schult. is mediated by inhibition of alpha glucosidase, protein glycation and stimulation of adipogenesis. Journal of Diabetes. 2015; July 7: 548-61. DOI: 10.1111/1753-0407.12216
21. Akanji MA, Olukolu SO, Kazeem MI. Leaf Extracts of Aerva lanata Inhibit the Activities of Type 2 Diabetes-Related Enzymes and Possess Antioxidant Properties. Oxidative Medicine and Cellular Longevity, 2018; Sept 2018: 3439048.doi: 10.1155/2018/3439048
22. Egamberdieva D, Mamedov N, Ovidi E, Tiezzi A, Craker L. Phytochemical and Pharmacological Properties of Medicinal Plants from Uzbekistan: A Review. Journal of Medicinally Active Plants. 2017; Oct 5; 2(5): 1-4. DOI: https://doi.org/10.7275/R5571969
23. Shakya AK. Medicinal plants: Future source of new drugs. International Journal of Herbal Medicine. 2016; June 4(4): 59-64. Chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.florajournal.com/archives/2016/vol4issue4/PartA/4-2-13-120.pdf
24. Maurya R, Singh G, Yadav PP. Antiosteoporotic agents from Natural sources. Studies in Natural Products Chemistry. 2008; Dec 35: 517-45. DOI:10.1016/S1572-5995(08)80013-0
25. Chopra A, Doiphode V. Ayurvedic medicine: Core concept, therapeutic principles and current relevance. Medical Clinics of North America. 2002; Jan 86(1): 75-89. DOI: 10.1016/s0025-7125(03)00073-7
26. Mahalik G, Sahoo S, Satapathy KB. Review on Pharmacological and Phytochemical Constituents of Aerva lanata (Linn) Juss. Ex. Schult. International Journal of Research and Analytical Reviews. 2019 June 6(2): 723-30. https://www.academia.edu/39519126/Review_on_pharmacological_and_phytochemical_constituents_of_Aerva_lanata_Linn_Juss_Ex_Schult
27. Bartha R. Fodder plants in the sahel zone of Africa. Welttforumverlog, Muchen. 1970.
28. Palmer J, Laliy TR. Amaranthaceae (Version 1), Flora of South Australia, 5th edition, edited by J Kellerman, State Herbarium of South Australia: Adelaide. 2011.
29. Alloui L, Rahamani Z, Dekmouche M, Djemoui D. Phytochemical analysis and antioxidant od Aerva javanica (Burm. F.) Juss Ex shult, Journal of Fundamental and Applied Science. 2013; May 12(1): 12-25.
https://www.ajol.info/index.php/jfas/article/view/247271
30. Anand SP, Doss A, Nandagopalan V. Qualitative and Quantative analysis of phytochemicals in aerva javanica (Burm. F.) shult. Acta Biomedica Scientia. 2014; Jan 1(2): 93-7.
https://www.researchgate.net/publication/276271743_Qualitative_and_quantitative_analysis_of_phytochemicals_in_Aerva_javanicaBurm_F_Shult
31. Harborne JB, Phytochemical method- A Guide to Modern Techniques of Plant Analysis. Chapman and Hall Limited, London. 1973.
32. Bhardwaj N, Siddiqui N. Phytochemicals Screening of Nigella sativa Seeds for Hypothoroid treatment. International Journal of Biological Pharmacy and Allied Science. 2020; Aug 9(8): 1939-44. https://doi.org/10.31032/IJBPAS/2020/9.8.5151
33. Nasir U, Irsha S. Evaluation of the antimicrobial activity of aqueous ethanolic and methanolic extracts of Nigella sativa (Kalaunji) against gram-positive and gram-negative bacterial isolates. pakistan Journal of Biochemistry and Molecular Biology. 2015 Nov 48: 92-6.
Chromeextension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.pjbmb.org.pk/images/PJBMBArchive/2015/PJBMB484Dec2015/02.pdf
34. Krishnaiah D, Devi T, Bono A, Sarbatly R. Studies on phytochemical constituents of six Malaysian medicinal plants. Journal of Medicinal Plants Research. 2009; Feb 3(2): 67-72.
Chromeextension://efaidnbmnnnibpcajpcglclefindmkaj/https://academicjournals.org/article/article1380370874_Krishnaiah%20et%20al.pdf
35. Kumar SR, Venkateshwar C, Samuel, Gangadhar RS. Phytochemical Screening of some compounds from leaf extracts of Holoptellia integrifellia (planch). International Journal of Engineering Science International. 2013; Aug 2: 65-70.
https://www.researchgate.net/publication/258218038_Phytochemical_Screening_of_some_compounds_from_plant_leaf_extracts_of_Holoptelea_integrifolia_Planch_and_Celestrus_emarginata_Grah_used_by_Gondu_tribes_at_Adilabad_District_Andhrapradesh_India_R_Suman
36. Malik SK, Ahmad M, Khan F. Qualitative and Quantitative Estimation of Terpenoid Contents in some important Plants of Punjab, Pakistan. Pakistan Journal of Science. 2017; June 69(2): 150-4. DOI:10.57041/pjs.v69i2.364
37. Bharadwaj N, Siddiqui N. Comperative Study of Phytochemical Analysis of Nigella Sativa and Flax Seeds used in Hypothyroid Treatment. World Journal of Pharmacy and Pharmaceutical Science. 2021; Feb 10(3): 1527-34.
https://www.wjpps.com/Wjpps_controller/abstract_id/14070
38. Velioglu YS, Mazza G, Gao L, Oomah BD. Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products. Journal of Agricultural Food Chemistry. 1998; Oct 46: 4113-7. DOI:10.1021/jf9801973
39. Hatano T, Edamatsu R, Hiramatsu M, Moti A, Fujita Y, Yasuhara T, Yoshida T, Okuda T. Effects of tannins and related polyphenols on superoxide anion radical, and on 1,1-diphenyl-2-picrylhydrazyl radical. Chemical Pharmaceutical Bulletin. 1990; May 37: 2016-21.DOI: 10.1248/cpb.38.1224
40. Saxena M, Saxena J, Nema R, Singh D, Gupta A. Phytochemistry of Medicinal Plants. Journal of Pharmacognosy and Phytochemistry. 2013; June 1(6): 168-82.
Chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.phytojournal.com/archives/2013/vol1issue6/PartA/26.pdf
41. Tanimura S, Kadomoto R, Tanak T, Zhang YJ, Kouno I, Kohno M. Supression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase 2/9 activity. Biochemical and Biophysical Research, Communicatio. 2005; May 330: 1306-13. DOI: 10.1016/j.bbrc.2005.03.116