ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): B.H. Kilarimath, V.G. Digge, S.S. Honnali, R.M. Sankangoud, P.C. Jalihal, Sonjoy Mandal

Email(s): digge1234@gmail.com

DOI: Not Available

Address: B.H. Kilarimath1, V.G. Digge2*, S.S. Honnali3, R.M. Sankangoud4, P.C. Jalihal5 and Sonjoy Mandal1
1Bapuji Pharmacy College, Davangere, Karnataka, India.
2Shivlingeshwar College of Pharmacy, Hasegaon, Maharashtra.
3KLE University’s College of Pharmacy, Hubli, Karnataka.
4KLES’s College of Pharmacy, Nipani, Karnataka.
5HSK College of Pharmacy, Bagalkot, Karnataka.
*Corresponding Author

Published In:   Volume - 4,      Issue - 5,     Year - 2011


ABSTRACT:
A series of 5-{2-[(substituted phenyl) amino] ethyl}-1, 3, 4-oxadiazole-2-thiol (IIIa-i) derivatives were synthesized by the reaction of 3-[(substituted phenyl) amino] propanehydrazide (IIa-i) with carbon disulphide in presence alc. KOH. Structures of the compounds were confirmed by the spectral data such as IR, 1H-NMR. All the synthesized compounds were tested against a panel of gram positive, gram negative bacteria and fungi using cup-plate-agar diffusion method. Some compounds shown promising activity.


Cite this article:
B.H. Kilarimath, V.G. Digge, S.S. Honnali, R.M. Sankangoud, P.C. Jalihal, Sonjoy Mandal. Synthesis and Antimicrobial Activity of Some Novel 2, 5-Di substituted 1, 3, 4-Oxadiazole Derivatives. Asian J. Research Chem. 4(5): May, 2011; Page 766-769.


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