Asian Journal of Research in Chemistry

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0974-4150 (Online)
0974-4169 (Print)


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Novel Synthesis and Biological Evaluation of some New Bipyrazolyl Benzenesulfonamides as possible Antimicrobial and Chemotherapeutic Agents

Author(s): Dilesh Indorkar, O.P. Chourasia, S.N. Limaye

Email(s): dileshindorkar@yahoo.in

DOI: Not Available

Address: Dilesh Indorkar*, O.P. Chourasia and S.N. Limaye
Department of Chemistry, Dr. H.S. Gour Central University, Sagar (M.P.) 470 003
*Corresponding Author

Published In:   Volume - 5,      Issue - 10,     Year - 2012

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ABSTRACT:
A series of functionalized bipyrazoles, fused bipyrazoles and other related heterocyclic systems have been synthesized.The key intermediate bipyrazoles have been prepared by cyclocondensation of the appropriate chalcone with4-hydrazinobenzenesulfonamide hydrochloride. The chemistry of the reactions employed in the synthesis of the target compounds together with their chemical behaviour, are discussed and the structures of the newly synthesized compounds have been confirmed by the IR and 1H and 13C NMR spectral data. All the synthesized compounds show weak anticancer activity and weak antimicrobial and antifungal activity against some bacteria and fungi.


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Cite this article:
Dilesh Indorkar, O.P. Chourasia, S.N. Limaye. Novel Synthesis and Biological Evaluation of some New Bipyrazolyl Benzenesulfonamides as possible Antimicrobial and Chemotherapeutic Agents. Asian J. Research Chem. 5(10): October, 2012; Page 1293-1299.

Cite(Electronic):
Dilesh Indorkar, O.P. Chourasia, S.N. Limaye. Novel Synthesis and Biological Evaluation of some New Bipyrazolyl Benzenesulfonamides as possible Antimicrobial and Chemotherapeutic Agents. Asian J. Research Chem. 5(10): October, 2012; Page 1293-1299.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2012-5-10-17


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Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
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