ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Jawed Akhtar, Jatin Prajapati, ShamimAhmad, Mohammad Mujahid, Gamal Osman Elhassan

Email(s): jawed.pharmacy@gmail.com

DOI: 10.5958/0974-4150.2015.00073.5   

Address: Jawed Akhtar1*, Jatin Prajapati2, ShamimAhmad1, Mohammad Mujahid1, Gamal Osman Elhassan3
1Translam Institute of Pharmaceutical Education and Research, Meerut, Uttar Pradesh-250001
2Astra Life Care Pvt. Ltd, Ahmedabad.
3Faculty of Pharmacy, Omdruman Islamic University, Khartoum, Sudan
*Corresponding Author

Published In:   Volume - 8,      Issue - 7,     Year - 2015


ABSTRACT:
A simple, precise, accurate and reproducible spectrophotometric method has been developed for simultaneous estimation of Lornoxicam (LXM) and Eperisone (EPE) by employing first order derivative zero crossing method in methanol. The first order derivative absorption at 264.5 nm (zero cross point of LXM) was used for quantification of EPE and 254 nm (zero cross point of EPE) for quantification of LXM. The linearity was established over the concentration range of 2-24 µg/ml with correlation coefficient 0.9987 and 0.997, respectively. The mean % recoveries were found to be in the range of 99.69 and 99.13 for LXM and EPE respectively. The developed method has been validated as per ICH guidelines and successfully applied to the estimation of LXM and EPE in their Synthetic Mixture.


Cite this article:
Jawed Akhtar, Jatin Prajapati, ShamimAhmad, Mohammad Mujahid, Gamal Osman Elhassan. Development and Validation of Derivative Spectrophotometric Method for Simultaneous Estimation of Lornoxicam and Eperisone in their Synthetic Mixture. Asian J. Research Chem. 8(7): July- 2015 ; Page 465-471. doi: 10.5958/0974-4150.2015.00073.5


Recomonded Articles:

Author(s): Vatchavai Bhaskara Raju, Bonthu Mohan Gandhi, Kamatham Srinivas Sumanth, Kolli Srinivas, Tupakula N Venkata Lakshmi Neeraja

DOI: 10.5958/0974-4150.2017.00030.X         Access: Open Access Read More

Author(s): Y. Padmavathi, Akari Anjali, Nayaka Raghavendra Babu, P Ravi Kumar

DOI: 10.5958/0974-4150.2017.00064.5         Access: Open Access Read More

Author(s): PA Jadhav, CS Raut, JP Bidada, BB Buwa, PN Dhabale, SC Dhawale

DOI:         Access: Open Access Read More

Author(s): R.K. Nanda, S.E. Potawale, V.V. Bhagwat, S.C.Hamane, R. S. Deshmukh

DOI:         Access: Open Access Read More

Author(s): VB Kshirsagar, UA Deokate, VB Bharkad, SS Khadabadi

DOI:         Access: Open Access Read More

Author(s): S. Ganapathy, G.V.H. Raju, D.G. Sankar, Pettla Y. Naidu

DOI:         Access: Open Access Read More

Author(s): Wankhede SB, Prakash A, Chitlange SS

DOI:         Access: Open Access Read More

Author(s): Mohd. Idris, S.N. Rasool, K.M. Varshney, S.K. Shukla, T.R. Baggi

DOI:         Access: Open Access Read More

Author(s): Shrivastava A, Nagori BP, Saini P, Issarani R, Gaur SS

DOI:         Access: Open Access Read More

Author(s): P. Nagaraju, Pasumarthy, NV Gopal, VDN Srinivas, SVN Padma

DOI:         Access: Open Access Read More

Author(s): Nagori BP, Shukla Shiv Shankar

DOI:         Access: Open Access Read More

Author(s): Ravi Pratap Pulla, B.S. Sastry, Y. Rajendra Prasad, N. Appala Raju

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Popular Articles


Recent Articles




Tags