Author(s):
Ashwini R. Ghorpade, Omkar U. Kale, Shivani R. Ghorpade, Bharatee P. Chaudhari, Vivekkumar K. Redasani
Email(s):
ashwinighorpade5220@gmail.com
DOI:
10.52711/0974-4150.2024.00023 
Address:
Ashwini R. Ghorpade*, Omkar U. Kale, Shivani R. Ghorpade, Bharatee P. Chaudhari, Vivekkumar K. Redasani
YSPMs, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe, Satara (415011)
*Corresponding Author
Published In:
Volume - 17,
Issue - 2,
Year - 2024
ABSTRACT:
A special surface modification approach serves as a basis for a colloidal drug delivery system (CDDS) that helps to preserve the surface's constraining function. An aquasome is a submicronic structure (diameter 60-300nm). In order to create a medication delivery method other than liposome technology, they attracted a lot of attention in an effort to resolve issues with these vesicles' stability in biological fluids. Pharmaceuticals are absorbed by the aquasome, a molecular carrier made of a ceramic core (colloidal precipitation) to which glassy carbohydrates are subsequently permitted to adsorb as a nanometer-thick surface coating. Pharmaceuticals and other biochemically reactive surface members with non-covalently attached immobilized elements are stabilized by the carbohydrate coating, which also serves as a dehydroprotectant. These are nanoparticulate carrier systems but instead of being simple nanoparticles these are three layered self-assembled structures, comprised of a solid phase nanocrystalline core coated with oligomeric film to which biochemically active molecules are adsorbed with or without modification. These structures are self-assembled by non-covalent and ionic bonds. A large number of In vitro and animal model studies have been used to investigate the physical characteristics of this enabling system. It can be used as a carrier for vaccinations, hemoglobin, medications, dyes, enzymes, and even genetic material, giving it a very broad range of applications.
Cite this article:
Ashwini R. Ghorpade, Omkar U. Kale, Shivani R. Ghorpade, Bharatee P. Chaudhari, Vivekkumar K. Redasani. Review on Vesicular Drug Delivery System: Aquasomes. Asian Journal of Research in Chemistry. 2024; 17(2):119-3. doi: 10.52711/0974-4150.2024.00023
Cite(Electronic):
Ashwini R. Ghorpade, Omkar U. Kale, Shivani R. Ghorpade, Bharatee P. Chaudhari, Vivekkumar K. Redasani. Review on Vesicular Drug Delivery System: Aquasomes. Asian Journal of Research in Chemistry. 2024; 17(2):119-3. doi: 10.52711/0974-4150.2024.00023 Available on: https://ajrconline.org/AbstractView.aspx?PID=2024-17-2-11
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